Systems level analysis of the Chlamydomonas reinhardtii metabolic network reveals variability in evolutionary co-conservation

Author:

Chaiboonchoe Amphun12345,Ghamsari Lila678910,Dohai Bushra12345,Ng Patrick11121310,Khraiwesh Basel12345ORCID,Jaiswal Ashish12345,Jijakli Kenan12345,Koussa Joseph12345,Nelson David R.12345,Cai Hong12345,Yang Xinping678910,Chang Roger L.148910,Papin Jason15161710,Yu Haiyuan11121310,Balaji Santhanam12345,Salehi-Ashtiani Kourosh12345

Affiliation:

1. Laboratory of Algal, Systems, and Synthetic Biology

2. Division of Science and Math

3. New York University Abu Dhabi and Center for Genomics and Systems Biology (CGSB)

4. New York University Abu Dhabi Institute

5. Abu Dhabi

6. Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology

7. Dana-Farber Cancer Institute, and Department of Genetics

8. Harvard Medical School

9. Boston

10. USA

11. Department of Biological Statistics and Computational Biology and Weill Institute for Cell and Molecular Biology

12. Cornell University

13. Ithaca

14. Department of Systems Biology

15. Department of Biomedical Engineering

16. University of Virginia

17. Charlottesville

Abstract

Topological and functional analyses of Chlamydomonas metabolic network offers insight into fluidity of gene-pair co-conservation dynamics.

Funder

Gordon and Betty Moore Foundation

Medical Research Council

National Institute of General Medical Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

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