Combining magnetic nanoparticle capture and poly-enzyme nanobead amplification for ultrasensitive detection and discrimination of DNA single nucleotide polymorphisms-Reference-Cited by-同舟云学术

Combining magnetic nanoparticle capture and poly-enzyme nanobead amplification for ultrasensitive detection and discrimination of DNA single nucleotide polymorphisms

Published:2019 Issue:3 Volume:11 Page:1195-1204
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Lapitan Lorico D. S.¹²³⁴⁵,Xu Yihan¹²³⁴,Guo Yuan⁶²³⁷^ORCID,Zhou Dejian¹²³⁴^ORCID

Affiliation:

1. School of Chemistry and Astbury Centre for Structural Molecular Biology

2. University of Leeds

3. Leeds LS2 9JT

4. UK

5. Department of Chemical Engineering

6. School of Food Science and Nutrition and Astbury Centre for Structural Molecular Biology

7. UK.

Abstract

An ultrasensitive sensor which combines magnetic capture and poly-enzyme nanobead amplification to quantify a low aM DNA target is developed.

Funder

University of Leeds

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2019/NR/C8NR07641C

Reference68 articles.

1. An Electrochemical Supersandwich Assay for Sensitive and Selective DNA Detection in Complex Matrices

2. DNA terminal structure-mediated enzymatic reaction for ultra-sensitive discrimination of single nucleotide variations in circulating cell-free DNA

3. A DNA Nanostructure-based Biomolecular Probe Carrier Platform for Electrochemical Biosensing

4. A multiplex nanoparticle-based bio-barcoded DNA sensor for the simultaneous detection of multiple pathogens

5. Using Commercially Available Personal Glucose Meters for Portable Quantification of DNA

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