Repurposing an antimicrobial peptide for the development of a dual ion channel/molecular receptor-like platform for metal ion detection-Reference-Cited by-同舟云学术

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Repurposing an antimicrobial peptide for the development of a dual ion channel/molecular receptor-like platform for metal ion detection

Published:2024 Issue:34 Volume:16 Page:15984-15994
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Mereuta Loredana¹,Park Jonggwan²,Park Yoonkyung³^ORCID,Luchian Tudor¹^ORCID

Affiliation:

1. Department of Physics, Alexandru I. Cuza University, 700506 Iasi, Romania

2. Department of Bioinformatics, Kongju National University, Kongju, 32588, Republic of Korea

3. Department of Biomedical Science and Research Center for Proteinaceous Materials (RCPM), Chosun University, Gwangju, 61452, Republic of Korea

Abstract

A system is proposed for inorganic Hg2+ sensing, based on modified alamethicin tethered with a thymine-rich peptide nucleic acid moiety, capable of generating ion channel oligomers whose activity is thymine–Hg2+–thymine complexation dependent.

Funder

National Research Foundation of Korea

Institute for Information and Communications Technology Promotion

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D4NR02433H

Reference74 articles.

1. Mercury and autoimmunity: implications for occupational and environmental health

2. Cognitive Performance of Children Prenatally Exposed to “Safe” Levels of Methylmercury

3. Mercury Toxicity and Treatment: A Review of the Literature

4. Past mercury exposure and current symptoms of nervous system dysfunction in adults of a First Nation community (Canada)

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