Organocatalytic asymmetric cascade bicyclization: access to chiral polycyclic bisindoles from 2-indolylmethanols and propargylic alcohols-Reference-Cited by-同舟云学术

Organocatalytic asymmetric cascade bicyclization: access to chiral polycyclic bisindoles from 2-indolylmethanols and propargylic alcohols

Published:2024 Issue:7 Volume:11 Page:2040-2046
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhu Wen-Run¹²,Su Qiong¹,Deng Xiao-Yi¹^ORCID,Ouyang Ze-Long¹,Weng Jiang¹^ORCID,Lu Gui¹^ORCID

Affiliation:

1. Guangdong Provincial Key Laboratory of New Drug Design and Evaluation, Guangdong Provincial Key Laboratory of Chiral Molecule and Drug Discovery, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, 510006, P.R. China

2. School of Pharmacy, Guangdong Pharmaceutical University, Guangzhou, 510006, P. R. China

Abstract

A chiral phosphoric acid-catalyzed asymmetric bis-cyclization of α-indolyl propargylic alcohols with 2-indolylmethanols was realized.

Funder

Guangdong Provincial Key Laboratory of Construction Foundation

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D3QO01558K

Reference51 articles.

1. Sustainable preparation of photoactive indole-fused tetracyclic molecules: a new class of organophotocatalysts

2. Indole-fused BN-heteroarenes as narrowband blue emitters for organic light-emitting diodes

3. Syntheses and medicinal chemistry of azepinoindolones: a look back to leap forward

4. Marine Indole Alkaloids: Potential New Drug Leads for the Control of Depression and Anxiety

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