Extracellular and Intracellular Signaling – a New Approach to Diseases and Treatments

Author:

Adams, Jr. James David1,Lien Eric J.1,Parker Keith2

Affiliation:

1. Department of Pharmacology and Pharmaceutical Sciences School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Los Angeles CA USA 90089

2. Department of Pharmaceutical Sciences (MPH102) BMED School of Pharmacy and Allied Health Sciences, Skaggs Building, Missoula MT USA 59812-1552

Abstract

Hormones, neurotransmitters, cytokines and a number of extracellular ligands participate in extracellular signaling mechanisms that modify cellular biochemistry. Intracellular ligands are involved in an array of intracellular signaling processes that increase or decrease the effects of extracellular ligands. Both extracellular and intracellular mechanisms are important in drug effects, maintaining health and treating chronic disease. The management of chronic diseases is becoming a very common process for many people. Many questions remain to be answered about chronic diseases. What causes them? Is it possible to prevent them? How are they best treated?

Publisher

The Royal Society of Chemistry

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