Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation-Reference-Cited by-同舟云学术

Integration of genetically engineered virus nanofibers and fibrin to form injectable fibrous neuron-rich hydrogels and enable neural differentiation

Published:2023 Issue:4 Volume:11 Page:802-815
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Chen Yingfan¹,Liu Xiangyu¹,Yang Mingying²^ORCID,Sun Weilian³,Mao Chuanbin¹⁴^ORCID

Affiliation:

1. School of Materials Science and Engineering, Zhejiang University, Zheda Road 38, Hangzhou 310027, Zhejiang, P. R. China

2. Institute of Applied Bioresource Research, College of Animal Science, Zhejiang University, Yuhangtang Road 866, Hangzhou 310058, China

3. Department of Periodontology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310009, P. R. China

4. Department of Chemistry & Biochemistry, Stephenson Life Science Research Center, Institute for Biomedical Engineering Science and Technology, University of Oklahoma, 101 Stephenson Parkway, Norman, Oklahoma 73019-5251, USA

Abstract

RGD-displaying phage, fibrin, and neural stem cells (NSCs) are integrated to form a fiber-like hydrogel, which promotes preferential differentiation of NSCs and serves as a nerve graft to repair the long-gap nerve defect by enhanced neurogenesis.

Funder

National Natural Science Foundation of China

Science and Technology Department of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/TB/D2TB01712A

Reference54 articles.

1. Advances and Future Applications of Augmented Peripheral Nerve Regeneration

2. Scaffolds for peripheral nerve repair and reconstruction