Ultrafast sensitivity-controlled and specific detection of extracellular vesicles using optical force with antibody-modified microparticles in a microflow system-Reference-Cited by-同舟云学术

Ultrafast sensitivity-controlled and specific detection of extracellular vesicles using optical force with antibody-modified microparticles in a microflow system

Published:2023 Issue:8 Volume:8 Page:1034-1042
ISSN:2055-6756
Container-title:Nanoscale Horizons
language:en
Short-container-title:Nanoscale Horiz.

Author:

Fujiwara Kana¹²³,Takagi Yumiko¹²,Tamura Mamoru²⁴^ORCID,Omura Mika²⁵,Morimoto Kenta²⁵,Nakase Ikuhiko²⁵^ORCID,Tokonami Shiho²³^ORCID,Iida Takuya¹²^ORCID

Affiliation:

1. Department of Physics, Graduate School of Science, Osaka Metropolitan University, 1-2, Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Japan

2. Research Institute for Light-induced Acceleration System (RILACS), Osaka Metropolitan University, 1-2, Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Japan

3. Department of Applied Chemistry, Graduate School of Engineering, Osaka Metropolitan University, 1-2, Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Japan

4. Department of Materials Engineering Science, Graduate School of Engineering Science, Osaka University, 1-3, Machikaneyama-cho, Toyonaka, Osaka 560-8531, Japan

5. Department of Biological Chemistry, Graduate School of Science, Osaka Metropolitan University, 1-2, Gakuen-cho, Naka-ku, Sakai, Osaka 599-8570, Japan

Abstract

We propose a detection method of 103–104 nanoscale extracellular vesicles secreted from cancer cells and distinguish their multiple membrane proteins using controlled optical force and microfluidic pressure only by 5 minutes laser irradiation.

Funder

Japan Society for the Promotion of Science

Japan Science and Technology Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NH/D2NH00576J

Reference36 articles.

1. Targeting Two-Pore Channels: Current Progress and Future Challenges

2. Liposomal Delivery Systems: Design Optimization and Current Applications

3. Human saliva, plasma and breast milk exosomes contain RNA: uptake by macrophages

4. Effects of gefitinib treatment on cellular uptake of extracellular vesicles in EGFR-mutant non-small cell lung cancer cells

5. Specificities of exosome versus small ectosome secretion revealed by live intracellular tracking of CD63 and CD9

Cited by 1 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. High-throughput light-induced immunoassay with milliwatt-level laser under one-minute optical antibody-coating on nanoparticle-imprinted substrate;npj Biosensing;2024-06-26