Delivery of TRAIL-expressing plasmid DNA to cancer cells in vitro and in vivo using aminoglycoside-derived polymers
Author:
Affiliation:
1. Chemical Engineering
2. Arizona State University
3. Tempe
4. USA
5. Department of Microbiology and Immunology
6. Medical University of South Carolina
7. Charleston
Abstract
Novel aminoglycoside-derived polymers for therapeutic gene delivery of the TRAIL-expressing plasmid to cancer cells in vitro and in vivo.
Funder
Arizona Biomedical Research Commission
National Institute of General Medical Sciences
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2019/TB/C9TB01286A
Reference72 articles.
1. Gene therapy and DNA delivery systems
2. Toxicity of cationic lipids and cationic polymers in gene delivery
3. Biological Gene Delivery Vehicles: Beyond Viral Vectors
4. Parallel Synthesis and Quantitative Structure–Activity Relationship (QSAR) Modeling of Aminoglycoside-Derived Lipopolymers for Transgene Expression
5. Discovery of Cationic Polymers for Non-Viral Gene Delivery Using Combinatorial Approaches
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