Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis,<i>in vitro</i>biological evaluation, and<i>in silico</i>ADMET analysis with molecular modeling simulations-Reference-Cited by-同舟云学术

Exploring novel derivatives of isatin-based Schiff bases as multi-target agents: design, synthesis,in vitrobiological evaluation, andin silicoADMET analysis with molecular modeling simulations

Published:2023 Issue:14 Volume:13 Page:9281-9303
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Hassan Ashraf S.¹^ORCID,Morsy Nesrin M.¹^ORCID,Aboulthana Wael M.²,Ragab Ahmed³^ORCID

Affiliation:

1. Organometallic and Organometalloid Chemistry Department, National Research Centre, Dokki 12622, Cairo, Egypt

2. Biochemistry Department, Biotechnology Research Institute, National Research Centre, Dokki 12622, Cairo, Egypt

3. Chemistry Department, Faculty of Science (Boys), Al-Azhar University, Nasr City, Cairo 11884, Egypt

Abstract

Recently, scientists developed a powerful strategy called “one drug-multiple targets” to discover vital and unique therapies to fight the most challenging diseases.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA00297G

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