Synthesis of novel tryptamine-based macrocycles using an Ugi 4-CR/microwave assisted click-cycloaddition reaction protocol
Author:
Affiliation:
1. Instituto de Química
2. Universidad Nacional Autónoma de México
3. Circuito Exterior S.N.
4. Ciudad Universitaria
5. Coyoacán
Abstract
A practical synthesis of novel tryptamine-based macrocycles using an Ugi 4-CR/click-cycloaddition sequential reaction protocol is described.
Funder
Consejo Nacional de Ciencia y Tecnología
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00067J
Reference38 articles.
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5. Macrocycles Are Great Cycles: Applications, Opportunities, and Challenges of Synthetic Macrocycles in Drug Discovery
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