Irisin recouples osteogenesis and osteoclastogenesis to protect wear-particle-induced osteolysis by suppressing oxidative stress and RANKL production-Reference-Cited by-同舟云学术

Irisin recouples osteogenesis and osteoclastogenesis to protect wear-particle-induced osteolysis by suppressing oxidative stress and RANKL production

Published:2021 Issue:17 Volume:9 Page:5791-5801
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Hu Sihan¹²,Xue Yuan¹²,He Jiachen¹,Chen Chichi¹,Sun Jie¹,Jin Yesheng¹²,Zhang Yuanshu¹²,Shi Qin¹^ORCID,Rui Yongjun²

Affiliation:

1. Department of Orthopedics, the First Affiliated Hospital of Soochow University, Orthopedics Institute of Soochow University, Medical College of Soochow University, Suzhou, Jiangsu, 215006, P. R. China

2. Department of Orthopedics, Wuxi Ninth People's Hospital affiliated to Soochow University, Wuxi, Jiangsu, 214026, P. R. China

Abstract

Irisin protected bone from Ti particle-induced osteolysis by recoupling osteoblastic formation and osteoclastic resorption.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Jiangsu Province

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00563D

Reference49 articles.

1. Trends in Joint Replacement Surgery in Patients with Rheumatoid Arthritis

2. Interactions between mammalian cells and nano- or micro-sized wear particles: Physico-chemical views against biological approaches

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4. Gentamicin in bone cement

5. Orthopedic implant cobalt-alloy particles produce greater toxicity and inflammatory cytokines than titanium alloy and zirconium alloy-based particles in vitro, in human osteoblasts, fibroblasts, and macrophages

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