A dual-responsive polyurethane nanocarrier for drug release triggered by intracellular GSH and NQO1 enzyme-Reference-Cited by-同舟云学术

A dual-responsive polyurethane nanocarrier for drug release triggered by intracellular GSH and NQO1 enzyme

Published:2024 Issue:24 Volume:15 Page:2513-2527
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Yang Shuai¹,Xie Jinhai¹,Wang Dongdong¹,Tian Shuangyu¹,Di Yaodong¹,Yan Lesan¹²^ORCID

Affiliation:

1. State Key Laboratory of Advanced Technology for Materials Synthesis and Processing, Biomedical Materials and Engineering Research Canter of Hubei Province, Wuhan University of Technology, Wuhan 430070, China

2. Wuhan University of Technology Advanced Engineering Technology Research Institute of Zhongshan City, Zhongshan 528400, China

Abstract

A dual-responsive polyurethane nanocarrier was developed to achieve specific and efficient drug release triggered by elevated glutathione levels and the NQO1 enzyme unique to tumor sites.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/PY/D4PY00320A

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