Simple droplet microfluidics platform for drug screening on cancer spheroids-Reference-Cited by-同舟云学术

Simple droplet microfluidics platform for drug screening on cancer spheroids

Published:2023 Issue:24 Volume:23 Page:5139-5150
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Parent Caroline¹^ORCID,Raj Melayil Kiran¹^ORCID,Zhou Ya¹,Aubert Vivian¹,Surdez Didier²^ORCID,Delattre Olivier³^ORCID,Wilhelm Claire¹^ORCID,Viovy Jean-Louis¹^ORCID

Affiliation:

1. Laboratoire Physico Chimie Curie, Institut Curie, CNRS, PSL Research University, 75005 Paris, France

2. Balgrist University Hospital, Faculty of Medicine, University of Zurich (UZH), Zurich, Switzerland

3. INSERM U830, Institut Curie, PSL Research University, 75005 Paris, France

Abstract

A novel microfluidics platform is introduced for generating tumoroids in droplets, enabling effective drug screening of chemotherapies on both cancer cell lines and patient-derived xenografts.

Funder

Agence Nationale de la Recherche

European Research Council

Fondation ARC pour la Recherche sur le Cancer

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D3LC00417A

Reference32 articles.

1. Tumor heterogeneity: Causes and consequences