Linker length in fluorophore–cholesterol conjugates directs phase selectivity and cellular localisation in GUVs and live cells-Reference-Cited by-同舟云学术

Linker length in fluorophore–cholesterol conjugates directs phase selectivity and cellular localisation in GUVs and live cells

Published:2019 Issue:40 Volume:9 Page:22805-22816
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

O' Connor Darragh¹²³⁴⁵^ORCID,Byrne Aisling¹²³⁴⁵,Keyes Tia E.¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemical Sciences

2. National Centre for Sensor Research

3. Dublin City University

4. Dublin 9

5. Ireland

Abstract

By inserting a hexyl linker between a BODIPY probe and cholesterol pendant, the localization of the probe at ternary phase separated GUVs switches from L_d to L_o domains with high specificity.

Funder

Science Foundation Ireland

European Regional Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA03905H

Reference70 articles.

1. Cholesterol homeostasis: a key to prevent or slow down neurodegeneration

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