Genome-scale metabolic models in translational medicine: the current status and potential of machine learning in improving the effectiveness of the models

Author:

Turanli Beste12,Gulfidan Gizem1,Aydogan Ozge Onluturk1,Kula Ceyda12,Selvaraj Gurudeeban34ORCID,Arga Kazim Yalcin125ORCID

Affiliation:

1. Marmara University, Faculty of Engineering, Department of Bioengineering, Istanbul, Turkey

2. Health Biotechnology Joint Research and Application Center of Excellence, Istanbul, Turkey

3. Concordia University, Centre for Research in Molecular Modeling & Department of Chemistry and Biochemistry, Quebec, Canada

4. Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha Dental College and Hospital, Department of Biomaterials, Bioinformatics Unit, Chennai, India

5. Marmara University, Genetic and Metabolic Diseases Research and Investigation Center, Istanbul, Turkey

Abstract

The use of genome scale metabolic models supported by machine learning from bench side to bed side.

Funder

Türkiye Bilimsel ve Teknolojik Araştırma Kurumu

Yükseköğretim Kurulu

Marmara Üniversitesi

Publisher

Royal Society of Chemistry (RSC)

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