On the thermodynamics of folding of an i-motif DNA in solution under favorable conditions
Author:
Affiliation:
1. Department of Pharmacy
2. University of Naples Federico II
3. Naples
4. Italy
Abstract
Differential scanning calorimetry and circular dichroism were used to unravel the folding thermodynamics of an i-motif DNA structure in solution under mildly acidic conditions that promote its formation.
Funder
Associazione Italiana per la Ricerca sul Cancro
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2021/CP/D1CP01779A
Reference46 articles.
1. Conformational changes of non-B DNA
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3. Stability and Cations Coordination of DNA and RNA 14-Mer G-Quadruplexes: A Multiscale Computational Approach
4. Chemical biology of non-canonical structures of nucleic acids for therapeutic applications
5. Noncanonical DNA Secondary Structures as Drug Targets: the Prospect of the i-Motif
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