Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir-Reference-Cited by-同舟云学术

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

Published:2020 Issue:26 Volume:11 Page:6736-6744
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Szymkuć Sara¹²³⁴,Gajewska Ewa P.¹²³⁴,Molga Karol¹²³⁴,Wołos Agnieszka¹²³⁴,Roszak Rafał¹²³⁴,Beker Wiktor¹²³⁴,Moskal Martyna¹²³⁴,Dittwald Piotr¹²³⁴,Grzybowski Bartosz A.¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. Polish Academy of Sciences

3. Warsaw 02-224

4. Poland

5. IBS Center for Soft and Living Matter

Abstract

A computer program for retrosynthetic planning helps develop multiple “synthetic contingency” plans for hydroxychloroquine and also routes leading to remdesivir, both promising but yet unproven medications against COVID-19.

Funder

Narodowe Centrum Nauki

Institute for Basic Science

Defense Advanced Research Projects Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC01799J

Reference35 articles.

1. Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro