Iridium(iii) complexes with 1,10-phenanthroline-based N^N ligands as highly selective luminescent G-quadruplex probes and application for switch-on ribonuclease H detection

Author:

Lu Lihua12345,Wang Wanhe5674,Yang Chao8910114,Kang Tian-Shu8910114,Leung Chung-Hang8910114,Ma Dik-Lung5674

Affiliation:

1. College of Chemistry and Pharmaceutical Sciences

2. Qingdao Agricultural University

3. Qingdao 266109

4. China

5. Department of Chemistry

6. Hong Kong Baptist University

7. Hong Kong

8. State Key Laboratory of Quality Research in Chinese Medicine

9. Institute of Chinese Medical Sciences

10. University of Macau

11. Macao

Abstract

A study was performed to investigate the relationship between molecular structure and G4 sensing ability for a series of iridium(iii) complexes. The complex7was used to construct a G4-based assay for RNase H.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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