Selective and sensitive spectrofluorimetric quantification of velpatasvir in presence of sofosbuvir. Application to their co-formulated tablet

Author:

El-Gamal Rania M.12345,Abdel-Gawad Sherif A.12345,Belal Fathalla F.678910,Moustapha Moustapha E.1112345

Affiliation:

1. Pharmaceutical Chemistry Department

2. College of Pharmacy

3. Prince Sattam Bin-Abdul Aziz University

4. Al-Kharj

5. Kingdom of Saudi Arabia

6. Department of Pharmaceutical Analytical Chemistry

7. Faculty of Pharmacy

8. Mansoura University

9. Mansoura

10. Egypt

11. Department of Chemistry

12. College of Science and Humanities

Abstract

A new sensitive, rapid and simple spectrofluorimetric method was utilized for the assessment of velpatasvir (VPS) in its bulk form as well as in its combined tablet with sofosbovir (SFV).

Funder

Prince Sattam bin Abdulaziz University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Reference15 articles.

1. Epidemiology of Hepatitis B and C Viruses: A Global Overview

2. PubChem (2018), https://pubchem.ncbi.nlm.nih.gov/compound/Velpatasvir#section=Top , accessed, 12 February 2018

3. Wikipedia (2018), https://en.wikipedia.org/wiki/Sofosbuvir , accessed, 12 February 2018

4. Drugs.com (2018), https://www.drugs.com/history/epclusa.html , accessed, 12 February 2018

5. Simple chromatographic and spectrophotometric determination of sofosbuvir in pure and tablet forms

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