A quinazoline-based HDAC inhibitor affects gene expression pathways involved in cholesterol biosynthesis and mevalonate in prostate cancer cells
Author:
Affiliation:
1. Auckland Cancer Society Research Centre
2. University of Auckland
3. New Zealand
4. Discipline of Nutrition and Dietetics
Abstract
Chronic inflammation can lead to the development of cancers and resolution of inflammation is an ongoing challenge.
Funder
Faculty of Medical and Health Sciences, University of Auckland
Publisher
Royal Society of Chemistry (RSC)
Subject
Molecular Biology,Biotechnology
Link
http://pubs.rsc.org/en/content/articlepdf/2016/MB/C5MB00554J
Reference64 articles.
1. The resolution of inflammation: the devil in the flask and in the details
2. Epigenetic protein families: a new frontier for drug discovery
3. Gene Expression Mapping of Histone Deacetylases and Co-factors and Correlation with Survival Time and 1H-HRMAS Metabolomic Profile in Human Gliomas
4. HDAC inhibitors in cancer biology: emerging mechanisms and clinical applications
5. The roles of TGFβ in the tumour microenvironment
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