Formal total synthesis of the akuammiline alkaloid (+)-strictamine

Author:

Xiao Tao1234,Chen Zhi-Tao1234,Deng Lin-Feng56784,Zhang Dan56784,Liu Xiao-Yu56784,Song Hao56784,Qin Yong56784ORCID

Affiliation:

1. School of Pharmaceutical Sciences and The Innovative Drug Research Centre

2. Chongqing University

3. Chongqing 401331

4. P. R. China

5. Key Laboratory of Drug Targeting and Drug Delivery Systems of the Ministry of Education

6. West China School of Pharmacy and State Key Laboratory of Biotherapy

7. Sichuan University

8. Chengdu 610041

Abstract

An asymmetric formal total synthesis of the akuammiline alkaloid (+)-strictamine is reported.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Reference67 articles.

1. CCLIV.—The alkaloids of Picralima Klaineana

2. Current Progress in the Chemistry and Pharmacology of Akuammiline Alkaloids

3. G. Adams and A. B.Smith , The chemistry of the akuammiline alkaloids , in The Alkaloids , ed. H.-J. Knolker , Elsevier , NewYork , 2016 , vol. 76, p. 171

4. Review of the phytochemical, pharmacological and toxicological properties of Alstonia Scholaris Linn. R. Br (Saptaparna)

5. Chinese Pharmacopoeia , ed. Committee of Chinese Pharmacopoeia , China People's Medical Publishing House , Beijing , 1977 , vol. 1, p. 245

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