Perfluoroalkylated Biomolecules for Medicinal Chemistry and Biological Studies

Abstract

For many years, it has been well established that the presence of a fluorine atom and/or a fluorinated group in molecules leads to active and selective drugs for certain diseases. With developments in this field, polyfluoroalkylated compounds for nuclear magnetic resonance (19F NMR) spectroscopy and magnetic resonance imaging (19F MRI) have been intensively studied in chemical biological investigations, imaging and diagnostics.