A Sugar Machine-Reference-Cited by-同舟云学术

A Sugar Machine

Published:2022-04-29 Issue: Volume: Page:80-98
ISSN:
Container-title:Sustainable and Functional Redox Chemistry
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Author:

Endo HIROFUMI¹,Rahman MD AZADUR²,Nokami TOSHIKI¹²³

Affiliation:

1. Department of Engineering, Graduate School of Sustainability Science, Tottori University 4-101 Koyamachominami Tottori city 680-8552 Tottori Japan tnokami@tottori-u.ac.jp

2. Department of Chemistry and Biotechnology, Graduate School of Engineering, Tottori University 4-101 Koyamachominami Tottori city 680-8552 Tottori Japan

3. Center for Research on Green Sustainable Chemistry, Faculty of Engineering, Tottori University 4-101 Koyamachominami Tottori city 680-8552 Tottori Japan

Abstract

A sugar machine for the automated electrochemical solution-phase synthesis of oligosaccharides has been developed. The machine enables the quantitative conversion of thioglycosides into glycosyl triflates that are highly reactive glycosylation intermediates and glycosylation reaction with thioglycosides as coupling partners. This one-pot process of chemical glycosylation can be repeated for multiple cycles until the target oligosaccharide is obtained. Total syntheses of biologically active oligosaccharides have been achieved by using the sugar machine.

Publisher

The Royal Society of Chemistry

Link

https://books.rsc.org/books/edited-volume/chapter-pdf/1713216/bk9781839162466-00080.pdf

Reference29 articles.

1. Strategies for chemoenzymatic synthesis of carbohydrates

2. Automated Chemical Oligosaccharide Synthesis: Novel Approach to Traditional Challenges

3. Electrochemical glycosylation method

4. Electrochemical glycosylation using phenyl S-glycosides

5. Anodic glycosylation from aryl thioglycosides