Gramicidin S-inspired antimicrobial cyclodextrin to disrupt gram-negative and gram-positive bacterial membranes-Reference-Cited by-同舟云学术

Gramicidin S-inspired antimicrobial cyclodextrin to disrupt gram-negative and gram-positive bacterial membranes

Published:2019 Issue:8 Volume:10 Page:1432-1437
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Yamamura Hatsuo¹²³⁴⁵^ORCID,Isshiki Kana¹²³⁴⁵,Fujita Yusuke¹²³⁴⁵,Kato Hisato⁶⁷⁸⁵^ORCID,Katsu Takashi⁶⁷⁸⁵,Masuda Kazufumi⁹⁷⁸⁵,Osawa Kayo¹⁰¹¹¹²¹³⁵,Miyagawa Atsushi¹²³⁴⁵

Affiliation:

1. Materials Science and Engineering

2. Graduate School of Engineering

3. Nagoya Institute of Technology

4. Nagoya 466-8555

5. Japan

6. School of Pharmacy

7. Shujitsu University

8. Okayama 703-8516

9. Graduate School of Clinical Pharmacy

10. Department of Biophysics

11. Kobe University

12. Graduate School of Health Sciences

13. Kobe 654-0142

Abstract

Microwave-assisted click reaction endowed cyclodextrin with amphiphilic structure leading to bacteriocidal membrane disruption, no development of resistance, and no haemolysis.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C9MD00229D

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