Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy-Reference-Cited by-同舟云学术

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Simultaneous visualization of the subfemtomolar expression of microRNA and microRNA target gene using HILO microscopy

Published:2017 Issue:9 Volume:8 Page:6670-6678
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Lin Yi-Zhen¹²³⁴,Ou Da-Liang⁵⁶⁷⁸⁴,Chang Hsin-Yuan¹²³⁴,Lin Wei-Yu¹²³⁴,Hsu Chiun⁹¹⁰⁸⁴¹¹,Chang Po-Ling¹²³⁴^ORCID

Affiliation:

1. Department of Chemistry

2. Tunghai University

3. Taichung 407

4. Taiwan

5. Graduate Institute of Oncology

6. College of Medicine

7. National Taiwan University

8. Taipei 100

9. Department of Internal Medicine

10. National Taiwan University Hospital

11. Department of Oncology

Abstract

In this study, we propose a sensitive imaging method for the direct probing of miR-10b and its target in fixed cells.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/SC/C7SC02701J

Reference52 articles.

1. Oncomirs — microRNAs with a role in cancer

2. OncomiRs: the discovery and progress of microRNAs in cancers

3. MicroRNAs in cancer: biomarkers, functions and therapy

4. MicroRNAs en route to the clinic: progress in validating and targeting microRNAs for cancer therapy

5. Tumor-targeted Delivery of Anti-microRNA for Cancer Therapy: pHLIP is Key

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