Novel mitochondria targeted copper(ii) complexes of ferrocenyl terpyridine and anticancer active 8-hydroxyquinolines showing remarkable cytotoxicity, DNA and protein binding affinity

Author:

Deka Banashree1234,Sarkar Tukki1234,Banerjee Samya1567,Kumar Arun89104,Mukherjee Sanjoy1112137,Deka Sasanka114154ORCID,Saikia Kandarpa K.161718194,Hussain Akhtar1234ORCID

Affiliation:

1. Department of Chemistry

2. Handique Girls’ College

3. Guwahati 781001

4. India

5. Johns Hopkins University

6. Baltimore

7. USA

8. Department of Inorganic and Physical Chemistry

9. Indian Institute of Science

10. Bangalore 560 012

11. School of Chemical Engineering

12. Purdue University

13. West Lafayette

14. University of Delhi

15. New Delhi 110007

16. Department of Bioengineering and Technology

17. GUIST

18. Gauhati University

19. Guwahati 781014

Abstract

Mixed-ligand ferrocenyl copper(ii) complexes target the mitochondria of cancer cells showing remarkable cytotoxicity against HeLa and MCF-7 cancer cells while being much less toxic to MCF-10A normal cells.

Funder

Department of Biotechnology , Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3