Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition studies and cellular imaging investigations-Reference-Cited by-同舟云学术

Synthesis of sulfonamide conjugates of Cu(ii), Ga(iii), In(iii), Re(v) and Zn(ii) complexes: carbonic anhydrase inhibition studies and cellular imaging investigations

Published:2015 Issue:11 Volume:44 Page:4859-4873
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Dilworth Jonathan R.¹²³⁴⁵,Pascu Sofia I.²⁶⁵,Waghorn Philip A.¹²³⁴⁵,Vullo Daniela⁷⁸⁹¹⁰¹¹,Bayly Simon R.¹²³⁴⁵,Christlieb Martin¹²³⁴⁵,Sun Xin¹²³⁴⁵,Supuran Claudiu T.⁷⁸⁹¹⁰¹¹

Affiliation:

1. Siemens Oxford Molecular Imaging Laboratory

2. Department of Chemistry

3. University of Oxford

4. Oxford

5. UK

6. University of Bath

7. University of Florence

8. NEUROFARBA Department

9. Pharmaceutical Sciences Section

10. 5019 Sesto Fiorentino

11. Italy

12. CRUK/MRC Gray Institute for Radiation Oncology and Biology

Abstract

New sulfonamides and their metal complexes are reported, with a focus on porphyrin derivatives for simultaneous cellular optical imaging, radiolabelling and Carbonic Anhydrase inhibition capabilities.

Funder

CHIST-ERA

Royal Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT03206C

Reference47 articles.

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2. Carbonic Anhydrase Inhibitors. Inhibition of Cytosolic Isozymes I and II and Transmembrane, Cancer-associated Isozyme IX with Anions

3. Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers

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