A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function-Reference-Cited by-同舟云学术

A red-shifted photochromic sulfonylurea for the remote control of pancreatic beta cell function

Published:2015 Issue:27 Volume:51 Page:6018-6021
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Broichhagen J.¹²³⁴,Frank J. A.¹²³⁴,Johnston N. R.⁵⁶⁷⁸⁹,Mitchell R. K.⁵⁶⁷⁸⁹,Šmid K.¹²³⁴,Marchetti P.¹⁰¹¹¹²¹³¹⁴,Bugliani M.¹⁰¹¹¹²¹³¹⁴,Rutter G. A.⁵⁶⁷⁸⁹,Trauner D.¹²³⁴,Hodson D. J.⁵⁶⁷⁸⁹

Affiliation:

1. Department of Chemistry and Center for Integrated Protein Science

2. LMU Munich

3. Munich

4. Germany

5. Section of Cell Biology and Functional Genomics

6. Department of Medicine

7. Imperial College London

8. London W12 0NN

9. UK

10. Department of Clinical and Experimental Medicine

11. Islet Cell Laboratory

12. University of Pisa

13. Pisa

14. Italy

Abstract

Heterocyclic azobenzene photoresponsive elements can be installed on sulfonylureas, yielding optical control over insulin release with yellow light.

Funder

Wellcome Trust

Medical Research Council

European Research Council

European Foundation for the Study of Diabetes

Diabetes UK

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC01224D

Reference23 articles.

1. Nutrient–secretion coupling in the pancreatic islet β-cell: recent advances

2. Mechanisms of Diabetic Complications

3. Systematic Review: Comparative Effectiveness and Safety of Oral Medications for Type 2 Diabetes Mellitus

4. Dynamics of insulin secretion and the clinical implications for obesity and diabetes

5. Photopharmacology: Beyond Proof of Principle

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