Dual-functional cyclometalated iridium imine NHC complexes: highly potent anticancer and antimetastatic agents

Author:

Tian Zhenzhen12345,Yang Yuliang12345,Guo Lihua12345ORCID,Zhong Genshen678910,Li Juanjuan12345,Liu Zhe12345ORCID

Affiliation:

1. Institute of Anticancer Agents Development and Theranostic Application

2. The Key Laboratory of Life-Organic Analysis and Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine

3. Department of Chemistry and Chemical Engineering

4. Qufu Normal University

5. Qufu 273165

6. Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine

7. School of Laboratory Medicine

8. Xinxiang Medical University

9. Xinxiang 453003

10. China

Abstract

Six cyclometalated iridium(iii) complexes have been synthesized and characterized. They showed strong anticancer and antimetastatic activity.

Funder

National Natural Science Foundation of China

Taishan Scholar Project of Shandong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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