Selective and clean synthesis of aminoalkyl-H-phosphinic acids from hypophosphorous acid by phospha-Mannich reaction-Reference-Cited by-同舟云学术

Selective and clean synthesis of aminoalkyl-H-phosphinic acids from hypophosphorous acid by phospha-Mannich reaction

Published:2020 Issue:36 Volume:10 Page:21329-21349
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Urbanovský Peter¹²³⁴,Kotek Jan¹²³⁴^ORCID,Císařová Ivana¹²³⁴,Hermann Petr¹²³⁴^ORCID

Affiliation:

1. Department of Inorganic Chemistry

2. Faculty of Science

3. Universita Karlova (Charles University)

4. Czech Republic

Abstract

Acetic acid was used as a new solvent for phospha-Mannich reaction leading to clear reaction mixtures and high yields of the aminoalkylphosphonous acids (AHPA), and hydroxymethylated species were suggested as key intermediates in the reaction.

Funder

Grantová Agentura České Republiky

Univerzita Karlova v Praze

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA03075A

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