Synthesis of axially chiral biaryl-2-carboxamides through Pd(<scp>ii</scp>)-catalyzed atroposelective C

Synthesis of axially chiral biaryl-2-carboxamides through Pd(ii)-catalyzed atroposelective C–H olefination

Published:2024 Issue:13 Volume:11 Page:3710-3716
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Jiang Bo-Yang¹,Zhou Gang¹,Jiang Ao-Lian²,Zhou Tao¹³^ORCID,Shi Bing-Feng¹³^ORCID

Affiliation:

1. Center of Chemistry for Frontier Technologies, Department of Chemistry, Zhejiang University, Hangzhou, Zhejiang, 310027, China

2. School of Biotechnology and Health Sciences, Wuyi University, Jiangmen, Guangdong, 529020, China

3. College of Material Chemistry and Chemical Engineering, Key Laboratory of Organosilicon Chemistry and Material Technology, Ministry of Education, Hangzhou Normal University, Hangzhou, Zhejiang, 311121, China

Abstract

A Pd(ii)-catalyzed atroposelective C–H olefination for the synthesis of axially chiral biaryl-2-carboxamides is reported.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Zhejiang Province

Hangzhou Normal University

Zhejiang University

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QO/D4QO00493K

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