Ni-Catalyzed electrophile driven regioselective arylative cyclization of ortho-functional diaryl acetylenes for the synthesis of pyridine and indene derivatives

Author:

Singam Maneesh Kumar Reddy12345,Nagireddy Attunuri12345,Rajesh Manda12345,Ganesh Veeramalla12345,Reddy Maddi Sridhar12345ORCID

Affiliation:

1. Department of OSPC

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad 500007

4. India

5. Academy of Scientific and Innovative Research

Abstract

A regioselective arylative cyclization of ortho functional diaryl acetylenes for the synthesis of selectively substituted diaryl pyridine and indene derivatives is accomplished through an electrophile driven alkyne polarization.

Funder

Council of Scientific and Industrial Research, India

Department of Science and Technology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference71 articles.

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2. A. Ding and H.Guo , in Comprehensive Organic Synthesis II , ed. P. Knochel , Elsevier , Amsterdam , 2nd edn, 2014 , pp. 891–938

3. Alkenylation of Arenes and Heteroarenes with Alkynes

4. Synthesis of heterocycles via transition-metal-catalyzed hydroarylation of alkynes

5. Nickel-Catalyzed Reductive Cyclizations and Couplings

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