Direct coupling of a free-flow isotachophoresis (FFITP) device with electrospray ionization mass spectrometry (ESI-MS)

Author:

Park J. K.123,Campos C. D. M12345,Neužil P.12367,Abelmann L.12389,Guijt R. M.1231011,Manz A.123

Affiliation:

1. Korea Institute of Science and Technology (KIST)-Europe

2. Campus e 7 1

3. Germany

4. State University of Campinas

5. Brazil

6. Central European Institute of Technology

7. Brno University of Technology

8. MESA+

9. University of Twente

10. School of Medicine and ACROSS

11. University of Tasmania

Abstract

The direct coupling of free-flow isotachophoresis device with an electrospray-ionization-mass-spectrometer allows continuous online detection without any sample preparation such as purification and labeling.

Funder

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Reference31 articles.

1. Metabolite profiling: from diagnostics to systems biology

2. High-resolution separations based on electrophoresis and electroosmosis

3. Capillary Zone Electrophoresis

4. Isotachophoretic analyses of anions at high pH

5. F. M. Everaerts , J. L.Beckers and T. P.Verheggen, Isotachophoresis: theory, instrumentation and applications, Elsevier, 2011

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