Synthesis and evaluation of anticancer activity of novel andrographolide derivatives-Reference-Cited by-同舟云学术

Synthesis and evaluation of anticancer activity of novel andrographolide derivatives

Published:2015 Issue:5 Volume:6 Page:898-904
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Devendar Ponnam¹²³⁴,Nayak Vadithe Lakshma⁵⁶⁷⁴,Yadav Dharmendra Kumar⁸⁹¹⁰⁴,Kumar Arigari Niranjana¹²³⁴,Kumar Jonnala Kotesh¹²³⁴,Satya Srinivas KVN¹²³⁴,Sridhar Balasubramanian¹¹⁶⁷⁴,Khan Feroz⁸⁹¹⁰⁴,Sastry Kakaraparthi Pandu¹²³⁴,Ramakrishna Sistla⁸⁹¹⁰⁴

Affiliation:

1. Natural Product Chemistry

2. CSIR – Central Institute of Medicinal and Aromatic Plants Research Centre

3. Hyderabad-500092

4. India

5. Medicinal Chemistry & Pharmacology

6. CSIR – Indian Institute of Chemical Technology

7. Hyderabad-500007

8. Metabolic and Structural Biology Department

9. CSIR – Central Institute of Medicinal and Aromatic Plants

10. Lucknow-226015

11. Centre for X-ray Crystallography

Abstract

Ceric ammonium nitrate facilitates andrographolide-3,19-O-acetal formation with alcohols. Anticancer active derivatives showed good docking scores in in silico.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C4MD00566J

Reference46 articles.

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4. Immunostimulant Agents from Andrographis paniculata

5. Inhibition of proprotein convertases-1, -7 and furin by diterpines of Andrographis paniculata and their succinoyl esters

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