Y1-receptor–ligand-functionalized ultrasmall upconversion nanoparticles for tumor-targeted trimodality imaging and photodynamic therapy with low toxicity

Author:

Yu Zhangsen12345,Xia Yuanzhi12345,Xing Jie12345,Li Zihou12345,Zhen Jianjun6789,Jin Yinhua6789,Tian Yuchen12345,Liu Chuang12345,Jiang Zhenqi12345,Li Juan12345,Wu Aiguo12345ORCID

Affiliation:

1. CAS Key Laboratory of Magnetic Materials and Devices

2. Key Laboratory of Additive Manufacturing Materials of Zhejiang Province

3. and Division of Functional Materials and Nanodevices

4. Ningbo Institute of Materials Technology and Engineering

5. Chinese Academy of Sciences

6. Department of Radiology

7. Ningbo No. 2 Hospital

8. Ningbo 315010

9. China

Abstract

We design and synthesize an ultrasmall and low toxicity MNPs(MC540)/DSPE-PEG-NPY nanocomposite with the multifunctions of targeted trimodality imaging and PDT.

Funder

National Natural Science Foundation of China

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Science and Technology Department of Zhejiang Province

Ningbo Municipal Bureau of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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