Rare-earth-doped fluoride nanoparticles with engineered long luminescence lifetime for time-gated in vivo optical imaging in the second biological window

Author:

Tan Meiling12345,del Rosal Blanca678910ORCID,Zhang Yuqi12345,Martín Rodríguez Emma1112131415ORCID,Hu Jie1617181411,Zhou Zhigang19204521,Fan Rongwei19204521,Ortgies Dirk H.1617181411ORCID,Fernández Nuria2223241725,Chaves-Coira Irene2627231728,Núñez Ángel2627231728,Jaque Daniel1617181411ORCID,Chen Guanying12345ORCID

Affiliation:

1. MIIT Key Laboratory of Critical Materials Technology for New Energy Conversion and Storage

2. School of Chemistry and Chemical Engineering & Key Laboratory of Micro-systems and Micro-structures

3. Ministry of Education

4. Harbin Institute of Technology

5. 150001 Harbin

6. Centre for Micro-Photonics

7. Faculty of Science

8. Engineering and Technology

9. Swinburne University of Technology

10. Hawthorn

11. Instituto Ramón y Cajal de Investigación Sanitaria

12. IRYCIS

13. Madrid 28034

14. Spain

15. Departamento de Física Aplicada

16. Departamento de Física de Materiales

17. Universidad Autónoma de Madrid

18. Madrid 28049

19. National Key Laboratory of Tunable Lasers

20. Institute of Optical-Electronics

21. People's Republic of China

22. Departamento de Fisiología

23. Facultad de Medicina

24. Avda. Arzobispo Morcillo 2

25. 28029 Madrid

26. Departamento de Anatomía

27. Histología y Neurociencia

28. Madrid

Abstract

We report on rare-earth-doped fluoride nanoparticles with a long lifetime and intense infrared emission in the second biological window for in vivo luminescence lifetime imaging.

Funder

Harbin Institute of Technology

National Natural Science Foundation of China

Ministerio de Economía y Competitividad

China Scholarship Council

Instituto de Salud Carlos III

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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