Evening primrose seed extract rich in polyphenols modulates the invasiveness of colon cancer cells by regulating the TYMS expression

Author:

Ciszewski Wojciech M.1ORCID,Włodarczyk Jakub2,Chmielewska-Kassassir Małgorzata3ORCID,Fichna Jakub2ORCID,Wozniak Lucyna A.3ORCID,Sobierajska Katarzyna1ORCID

Affiliation:

1. Department of Molecular Cell Mechanisms, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland

2. Department of Biochemistry, Medical University of Lodz, Mazowiecka 6/8, 92-215 Lodz, Poland

3. Department of Structural Biology, Medical University of Lodz, Zeligowskiego 7/9, 90-752, Lodz, Poland

Abstract

Natural polyphenols are plant metabolites exhibiting a broad range of biological activities.

Funder

Ministerstwo Nauki i Szkolnictwa Wyższego

Narodowe Centrum Nauki

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Reference62 articles.

1. J.Ferlay , M.Ervik , F.Lam , M.Colombet , L.Mery , M.Piñeros , A.Znaor , I.Soerjomataram and F.Bray , Global Cancer Observatory: Cancer Today , International Agency for Research on Cancer , Lyon, France , 2020

2. 5-Fluorouracil: mechanisms of action and clinical strategies

3. Thymidylate Synthase Expression in Hepatic Tumors Is a Predictor of Survival and Progression in Patients With Resectable Metastatic Colorectal Cancer

4. Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism

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