Quantifying the force in flow-cell based single-molecule stretching experiments-Reference-Cited by-同舟云学术

Quantifying the force in flow-cell based single-molecule stretching experiments

Published:2021 Issue:37 Volume:13 Page:15916-15927
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Liang Jialun¹²,Li Jiaxi¹²,Zhong Zhensheng¹²,Rujiralai Thitima³^ORCID,Ma Jie¹²^ORCID

Affiliation:

1. School of Physics, Sun Yat-sen University, Guangzhou 510275, Guangdong, China

2. State Key Laboratory of Optoelectronic Materials and Technologies, Sun Yat-sen University, Guangzhou 510275, Guangdong, China

3. Division of Physical Science, Faculty of Science, Prince of Songkla University, Hat Yai, Songkhla, 90112, Thailand

Abstract

A fully calibrated flow-cell can measure the single-molecule force in pN precision over 0–110 pN. Based on the “bead-spring chain” model and theory of fluid mechanics, the theoretical calculated forces are in good agreement with experiments.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Guangdong Province

Science and Technology Planning Project of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D1NR04748E

Reference64 articles.

1. Direct Observation of the Three-State Folding of a Single Protein Molecule

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