Partitioning of caffeine in lipid bilayers reduces membrane fluidity and increases membrane thickness

Author:

Khondker Adree1234,Dhaliwal Alexander1234,Alsop Richard J.1234,Tang Jennifer1234,Backholm Matilda12345,Shi An-Chang1234ORCID,Rheinstädter Maikel C.1234ORCID

Affiliation:

1. Department of Physics and Astronomy

2. McMaster University

3. Hamilton

4. Canada

5. Department of Applied Physics

Abstract

Caffeine partitions in lipid membranes in the head to tail interface and leads to a thickening and defluidification.

Funder

Natural Sciences and Engineering Research Council of Canada

McMaster University

Canada Foundation for Innovation

Ontario Ministry of Economic Development and Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

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