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Transition-metal-free and facile synthesis of 3-alkynylpyrrole-2,4-dicarboxylates from methylene isocyanides and propiolaldehyde

  • Published:2021 Issue:36 Volume:45 Page:16430-16433
  • ISSN:1144-0546
  • Container-title:New Journal of Chemistry
  • language:en
  • Short-container-title:New J. Chem.

Author:

Huo Xiaoli12,Chen Xiaojuan1,Yu Liya1,Zhang Chong12,Zeng Linghui12,Zhu Huajian12ORCID,Shao Jiaan12,Fu Liping3,Zhang Jiankang12ORCID

Affiliation:

1. School of Medicine, Zhejiang University City College, Hangzhou, Zhejiang 310015, PR China

2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, PR China

3. Department of Pharmacy, Shaoxing Hospital of Traditional Chinese Medicine, Shaoxing, Zhejiang 312000, PR China

Abstract

A transition-metal-free, facile and efficient method for the synthesis of 3-alkynylpyrrole-2,4-dicarboxylates was developed.

Funder

National Natural Science Foundation of China

Shaoxing Bureau of Science and Technology

Department of Health of Zhejiang Province

Hangzhou Science and Technology Bureau

Zhejiang Province Public Welfare Technology Application Research Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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