Enzyme-activatable fluorescent probes for β-galactosidase: from design to biological applications

Author:

Yao Yongkang12345,Zhang Yutao12345,Yan Chenxu12345ORCID,Zhu Wei-Hong12345ORCID,Guo Zhiqian12345ORCID

Affiliation:

1. Key Laboratory for Advanced Materials

2. Institute of Fine Chemicals

3. Feringa Nobel Prize Scientist Joint Research Center

4. Frontiers Science Center for Materiobiology and Dynamic Chemistry

5. School of Chemistry and Molecular Engineering

Abstract

This review highlights the molecular design strategy of β-galactosidase-activatable probes from turn-on mode to ratiometric mode, from ACQ to AIE-active probes, from NIR-I to NIR-II imaging and dual-mode of chemo-fluoro-luminescence imaging.

Funder

National Natural Science Foundation of China

Shanghai Municipal Education Commission

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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