Preparation and solid-state characterization of dapsone pharmaceutical cocrystals through the supramolecular synthon strategy-Reference-Cited by-同舟云学术

Preparation and solid-state characterization of dapsone pharmaceutical cocrystals through the supramolecular synthon strategy

Published:2021 Issue:38 Volume:23 Page:6690-6702
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Zhao Chenyang¹,Li Wanya¹,Li Zhonghua¹,Hu Weiguo¹²,Zhang Suoqing¹²,Wu Songgu¹^ORCID

Affiliation:

1. State Key Laboratory of Chemical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, P. R. China

2. North China Pharmaceutical Group Co., Ltd., Shijiazhuang, P. R. China

Abstract

Based on the design concept of supramolecular synthons, “–NH2⋯Npyridine” was used to prepare cocrystals of DAP: (1 : 1) and (2 : 1) DAP-PYR, which could be transformed into each other by mechanochemistry.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CE/D1CE00945A

Reference47 articles.

1. Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

2. Pharmaceutical cocrystals and poorly soluble drugs

3. Generation of 1:1 Carbamazepine:Nicotinamide cocrystals by spray drying

4. Pharmaceutical particle technologies: An approach to improve drug solubility, dissolution and bioavailability

5. Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications

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