Design, synthesis, biological activities and 3D-QSAR studies of quinazolinone derivatives containing hydrazone structural units
Author:
Affiliation:
1. College of Pharmacy
2. Guizhou University
3. Guiyang 550025
4. China
5. State Key Laboratory of Functions and Application of Medicinal Plants
6. Center for R&D of Fine Chemicals of Guizhou University
7. Guiyang
Abstract
A series of novel quinazolinone derivatives containing hydrazone structural units were synthesized and their antitumour activities were evaluated.
Funder
National Natural Science Foundation of China
State Key Laboratory of Functions and Applications of Medicinal Plants
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2021/NJ/D0NJ05450J
Reference31 articles.
1. Synthesis, Antiproliferative, and Antioxidant Evaluation of 2-Pentylquinazolin-4(3H)-one(thione) Derivatives with DFT Study
2. The molecular basis of targeting protein kinases in cancer therapeutics
3. Synthesis and anticancer activities of 4-(4-substituted piperazin)-5,6,7-trialkoxy quinazoline derivatives
4. Design, synthesis, and biological evaluation studies of novel quinazolinone derivatives as anticonvulsant agents
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