Discrimination of enantiomers of amides with two stereogenic centers enabled by chiral bisthiourea derivatives using 1H NMR spectroscopy

Author:

Zhang Hanchang1234,Zhao Hongmei56784,Wen Jie1234,Zhang Zhanbin1234,Stavropoulos Pericles9101112,Li Yanlin1234,Ai Lin1234ORCID,Zhang Jiaxin1234

Affiliation:

1. College of Chemistry

2. Beijing Normal University

3. Beijing 100875

4. P. R. China

5. State Key Laboratory of Information Photonics and Optical Communications

6. School of Science

7. Beijing University of Posts and Telecommunications

8. Beijing 100876

9. Department of Chemistry

10. Missouri University of Science and Technology

11. Rolla

12. USA

Abstract

Enantiomers of amides with two stereogenic centers have been effectively discriminated in the presence of chiral bisthiourea derivatives as chiral solvating agents by 1H NMR spectroscopy.

Funder

Beijing Normal University

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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