Core–shell stability of nanoparticles plays an important role for overcoming the intestinal mucus and epithelium barrier-Reference-Cited by-同舟云学术

Core–shell stability of nanoparticles plays an important role for overcoming the intestinal mucus and epithelium barrier

Published:2016 Issue:35 Volume:4 Page:5831-5841
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Liu Min¹²³⁴⁵,Wu Lei¹²³⁴⁵,Zhu Xi¹²³⁴⁵,Shan Wei¹²³⁴⁵,Li Lian¹²³⁴⁵,Cui Yi¹²³⁴⁵,Huang Yuan¹²³⁴⁵

Affiliation:

1. Key laboratory of Drug Targeting and Drug Delivery System (Ministry of Education)

2. West China School of Pharmacy

3. Sichuan University

4. Chengdu 610041

5. P. R. China

Abstract

The stability of the core–shell structure plays an important role in the nanoparticles ability to overcome both the mucus and epithelium absorption barrier.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2016/TB/C6TB01199C

Reference44 articles.

1. Overcoming the challenges in administering biopharmaceuticals: formulation and delivery strategies

2. Overcoming the Diffusion Barrier of Mucus and Absorption Barrier of Epithelium by Self-Assembled Nanoparticles for Oral Delivery of Insulin

3. Efficient mucus permeation and tight junction opening by dissociable “mucus-inert” agent coated trimethyl chitosan nanoparticles for oral insulin delivery

4. Goblet cell-targeting nanoparticles for oral insulin delivery and the influence of mucus on insulin transport

5. Mucus-penetrating nanoparticles for drug and gene delivery to mucosal tissues

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