Identifying the cellular targets of natural products using T7 phage display

Author:

Piggott Andrew M.1234ORCID,Karuso Peter1234

Affiliation:

1. Department of Chemistry and Biomolecular Sciences

2. Macquarie University

3. Sydney

4. Australia

Abstract

A description of the T7 phage biopanning procedure is provided with tips and advice suitable for setup in a chemistry laboratory.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference96 articles.

1. Natural products: A continuing source of novel drug leads

2. D. J. Newman and G. M.Cragg, in Natural Products: Discourse, Diversity, and Design, ed. A. Osbourn, R. J. Goss and G. T. Carter, John Wiley & Sons, Inc, Hoboken, NJ, USA, 2014, ch. 21, pp. 397–411

3. Cytotoxic Furanosesterterpenes from a Marine Sponge Psammocinia sp.

4. Five-membered ring systems: furans and benzofurans

5. Marine natural products

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