Synthesis of 1-(β-coumarinyl)-1-(β-indolyl)trifluoroethanols through regioselective Friedel–Crafts alkylation of indoles with β-(trifluoroacetyl)coumarins catalyzed by Sc(OTf)3-Reference-Cited by-同舟云学术

Synthesis of 1-(β-coumarinyl)-1-(β-indolyl)trifluoroethanols through regioselective Friedel–Crafts alkylation of indoles with β-(trifluoroacetyl)coumarins catalyzed by Sc(OTf)3

Published:2020 Issue:24 Volume:10 Page:13929-13935
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Shi Lijun¹²³⁴^ORCID,Liu Ying¹²³⁴,Wang Caixia¹²³⁴,Yuan Xinxin⁵²³⁴^ORCID,Liu Xiaobiao¹²³⁴,Wu Lulu¹²³⁴,Pan Zhenliang¹²³⁴,Yu Qicheng⁶²³⁴,Xu Cuilian¹²³⁴,Yang Guoyu¹²³⁴

Affiliation:

1. School of Science

2. Henan Agricultural University

3. Zhengzhou 450002

4. P. R. China

5. College of Resource and Environment

6. College of Animal Science and Veterinary Medicine

Abstract

A Friedel–Crafts alkylation of indoles with β-(trifluoroacetyl)coumarins catalyzed by Sc(OTf)₃ to afford 1-(β-coumarinyl)-1-(β-indolyl)trifluoroethanols in a short time and high yield was developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/RA/D0RA01237H

Reference97 articles.

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