Parallel [TG(GA)3]n-homoduplexes/thioflavin T: an intense and stable fluorescent indicator for label-free biosensing
Author:
Affiliation:
1. School of Chemistry & Chemical Engineering
2. Key laboratory of Analytical Chemistry for Life Science of Shaanxi Province
3. Shaanxi Normal University
4. Xi'an 710062
5. China
6. College of Food Engineering and Nutritional Science
Abstract
Compared with the G-quadruplex/ThT fluorescent system, parallel [TG(GA)3]n-dsDNA/ThT is a stable and strong fluorescent indicator for label-free biosensing.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/AN/C9AN01856E
Reference35 articles.
1. Interaction of Thioflavin T with Amyloid Fibrils: Fluorescence Quantum Yield of Bound Dye
2. Molecular Rotors: What Lies Behind the High Sensitivity of the Thioflavin-T Fluorescent Marker
3. Thioflavin-T for Amyloid Detection
4. Development of Tau Aggregation Inhibitors for Alzheimer's Disease
5. Thioflavin T as an Efficient Inducer and Selective Fluorescent Sensor for the Human Telomeric G-Quadruplex DNA
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