New imaging reagents for lipid dense regions in live cells and the nucleus in fixed MCF-7 cells
Author:
Affiliation:
1. Organic Chemistry Division
2. National Chemical Laboratory
3. Pune
4. India
5. Chromatin and Disease Laboratory
6. National Center for Cell Science
Abstract
Specific imaging of lipid dense regions of live MCF-7 cells is achieved with two new Ru(ii)-polypyridyl complexes 1 and 2. These visible light excitable reagents are stable towards photo-bleaching and large Stokes shifts are observed. Interestingly, these reagents were localized in the cell nucleus in PFA fixed MCF-7 cells.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB01309G
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