A systems biology and proteomics-based approach identifies SRC and VEGFA as biomarkers in risk factor mediated coronary heart disease

Author:

V. Alexandar1234,Nayar Pradeep G.56234,Murugesan R.1234,S. Shajahan7894,Krishnan Jayalakshmi7894,Ahmed Shiek S. S. J.101234

Affiliation:

1. Faculty of Allied Health Sciences

2. Chettinad Academy of Research and Education

3. Kelambakkam 603 103

4. India

5. Department of Cardiology

6. Chettinad Super Specialty Hospital

7. Department of Life Sciences

8. Central University of Tamil Nadu

9. Thiruvarur

10. Drug Discovery Lab

Abstract

We propose a novel systems biology approach that relates causative genes, interactomes and pathways to elucidate the risk factors mediating the molecular mechanisms and biomarkers of coronary heart disease for feasible diagnosis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Reference50 articles.

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4. Endothelin receptor antagonists in pulmonary arterial hypertension

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